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St. Joseph's is located near the intersection of US Highways 40 and 41.

From I-70, take exit 7 and go north on US 41 (3rd Street) about 2.5 miles.  Turn right on Poplar, go down two blocks and turn left onto 5th Street.  St. Joseph's is two blocks down on left.

From US 40 (Wabash Avenue), turn south onto 6th Street, go down two blocks and turn right on Walnut, then down one block and right onto 5th Street.  St. Joseph's is on the left.

Note: Walnut, 5th and 6th are all one-way streets